Evidence-based Toxicology
Learn systematic review and meta-analysis in toxicology. Explore quality assurance, validation, and biometrical tools for evidence-based approaches.
Learn systematic review and meta-analysis in toxicology. Explore quality assurance, validation, and biometrical tools for evidence-based approaches.
This course introduces learners to Evidence-based Toxicology (EBT), a revolutionary approach in regulatory safety sciences. Students will explore the shortcomings of current toxicity testing methods and learn how EBT can overcome these challenges. The curriculum covers systematic reviews, meta-analyses, risk of bias assessment, quality assurance, and validation of alternative methods. Through lectures, quizzes, and practical assignments, learners will gain skills in applying evidence-based approaches to toxicology research and decision-making.
4.7
(114 ratings)
9,660 already enrolled
Instructors:
English
21 languages available
Powered by
What you'll learn
Understand the principles and applications of Evidence-based Toxicology (EBT)
Learn to conduct systematic reviews and meta-analyses in toxicology
Explore risk of bias assessment and quality assurance in toxicological studies
Understand the validation process for alternative toxicity testing methods
Apply biometrical tools and statistical approaches in evidence-based toxicology
Examine the reproducibility crisis in science and how EBT can address it
Skills you'll gain
This course includes:
9 Hours PreRecorded video
9 assignments
Access on Mobile, Tablet, Desktop
FullTime access
Shareable certificate
Closed caption
Get a Completion Certificate
Share your certificate with prospective employers and your professional network on LinkedIn.
Created by
Provided by
Top companies offer this course to their employees
Top companies provide this course to enhance their employees' skills, ensuring they excel in handling complex projects and drive organizational success.
There are 7 modules in this course
This comprehensive course introduces students to Evidence-based Toxicology (EBT), a revolutionary approach in regulatory safety sciences. The curriculum covers the history and principles of EBT, systematic review and meta-analysis methodologies, risk of bias assessment, quality assurance, and validation of alternative methods. Students will learn to apply evidence-based approaches to toxicology research and decision-making, exploring topics such as causation vs. correlation, mechanistic toxicology, and the reproducibility crisis in science. Through a combination of video lectures, readings, quizzes, and a practical systematic review assignment, learners will gain hands-on experience in applying EBT principles to real-world toxicology challenges.
Introduction & Shortcomings of Current Approaches
Module 1 · 2 Hours to complete
History and Causation
Module 2 · 3 Hours to complete
Systematic Review and Meta-Analysis
Module 3 · 3 Hours to complete
Risk of Bias & Application to Test Methods Comparison
Module 4 · 2 Hours to complete
Quality Assurance, Good Practices, and Validation
Module 5 · 3 Hours to complete
Biometrical Tools & Future Perspectives
Module 6 · 2 Hours to complete
Summative Assessment - Systematic Review Assignment
Module 7 · 2 Hours to complete
Fee Structure
Payment options
Financial Aid
Instructors
Doerenkamp-Zbinden Chair for Evidence-based Toxicology at Johns Hopkins University
Thomas Hartung is the Doerenkamp-Zbinden Chair for Evidence-based Toxicology with a joint appointment in Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health. He also serves as a Professor of Pharmacology and Toxicology at the University of Konstanz, Germany. As the Director of the Centers for Alternatives to Animal Testing (CAAT) at both institutions, he leads initiatives aimed at advancing non-animal testing methods and promoting evidence-based toxicology. Hartung is known for his work on the Human Toxome project, which seeks to improve toxicity testing methodologies through innovative approaches, including organoid cultures and artificial intelligence. He previously headed the European Commission’s Center for the Validation of Alternative Methods (ECVAM) and has authored over 490 scientific publications, contributing significantly to the fields of toxicology and pharmacology. His research focuses on integrating big data and AI into predictive toxicology, aiming to enhance public health outcomes through improved testing strategies.
Research Associate at Johns Hopkins University
Lena Smirnova is a Research Associate at the Center for Alternatives to Animal Testing at the Johns Hopkins Bloomberg School of Public Health. Her research primarily focuses on developmental neurotoxicity and the role of microRNA in gene-environment interactions related to neurodevelopment and neurodegeneration. From 2007 to 2012, she worked as a Postdoctoral researcher at the Federal Institute of Risk Assessment in Berlin, Germany, where she coordinated a pre-validation study in inhalation toxicology while also researching neurotoxicology. Lena earned her PhD in Neuroscience from Charité – Universitätsmedizin Berlin in 2007, concentrating on microRNA's role in neural development and stem cell specification. She graduated from the International Sakharov Environmental University in Minsk, Belarus, in 2002, specializing in Radiobiology and Environmental Medicine. In addition to her research, Lena is involved in educational initiatives aimed at promoting modern toxicology methodologies.
Testimonials
Testimonials and success stories are a testament to the quality of this program and its impact on your career and learning journey. Be the first to help others make an informed decision by sharing your review of the course.
4.7 course rating
114 ratings
Frequently asked questions
Below are some of the most commonly asked questions about this course. We aim to provide clear and concise answers to help you better understand the course content, structure, and any other relevant information. If you have any additional questions or if your question is not listed here, please don't hesitate to reach out to our support team for further assistance.