Study MRI fundamentals, from quantum mechanics principles to medical imaging protocols and diagnostic applications.
Study MRI fundamentals, from quantum mechanics principles to medical imaging protocols and diagnostic applications.
Delve into the fascinating world of Magnetic Resonance Imaging (MRI) with this advanced 6-week course. Designed for those with a strong physics background, this course covers the fundamental principles of MRI, from the basics of Nuclear Magnetic Resonance (NMR) to advanced image reconstruction techniques. You'll explore the physics of spin dynamics, magnetic resonance, excitation, and relaxation. The curriculum also covers MR spectroscopy, functional MRI, and the use of contrast agents. By the end of the course, you'll understand the mechanisms behind tissue contrast in MRI, the inner workings of MRI scanners, and how to select appropriate imaging modalities for specific biomedical applications. This course bridges the gap between physics and life sciences, demonstrating the crucial role of physics in advancing biomedical research and clinical diagnostics.
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English
English
What you'll learn
Understand the fundamental physics principles of Nuclear Magnetic Resonance (NMR) and MRI
Analyze the behavior of spins in magnetic fields and the concepts of excitation and relaxation
Explore MR spectroscopy and its applications in molecular analysis
Master the principles of MRI image formation and reconstruction techniques
Understand various MRI contrast mechanisms, including BOLD fMRI and contrast agents
Learn to select appropriate MRI techniques for specific biomedical applications
Skills you'll gain
This course includes:
PreRecorded video
Graded assignments, exams
Access on Mobile, Tablet, Desktop
Limited Access access
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There are 6 modules in this course
This advanced course offers a comprehensive exploration of Magnetic Resonance Imaging (MRI) principles and applications in biomedical imaging. The curriculum is structured to cover the physics underlying MRI, starting from the basics of spin dynamics and the Boltzmann distribution to complex topics like MR spectroscopy and functional MRI. Students will learn about the Bloch equations, which describe the behavior of nuclear magnetization, and understand how they relate to MRI contrast mechanisms. The course delves into image formation principles, including k-space concepts and echo formation. Advanced topics such as BOLD fMRI and the use of contrast agents are also covered. Throughout the course, emphasis is placed on understanding how physical principles translate into biomedical applications, enabling students to critically evaluate the promises and limitations of different MRI techniques.
Introduction to biological magnetic resonance (MR)
Module 1
Excitation of spins, Relaxation, the Basis of MR contrast
Module 2
MR spectroscopy
Module 3
From Fourier to image: principles of MR image formation
Module 4
Basic MRI contrast mechanisms, BOLD fMRI, contrast agents
Module 5
Advanced contrast mechanisms & overview of imaging modalities
Module 6
Fee Structure
Instructor
2 Courses
Pioneer in Biomedical Imaging and Neuroenergetics
Rolf Gruetter is a Professor at École polytechnique fédérale de Lausanne (EPFL) and the head of the Laboratory for Functional and Metabolic Imaging. He has been instrumental in advancing biomedical imaging methods and instrumentation, particularly in the fields of magnetic resonance and neuroenergetics. Gruetter received his undergraduate and graduate degrees in Physics and Biophysics from ETH Zurich, followed by a postdoctoral fellowship at Yale University. Since joining EPFL in 2005, he has focused on developing techniques for non-invasive measurement of brain metabolism, contributing significantly to our understanding of neurochemistry and metabolic processes. His major works include pioneering studies on the in vivo measurement of brain metabolites using advanced NMR spectroscopy techniques, which have implications for understanding brain function and disorders. Gruetter's research interests encompass mathematical modeling of metabolism, spin physics, and the application of imaging methods to study energy metabolism in the brain. His contributions have earned him recognition as a senior fellow of the International Society for Magnetic Resonance in Medicine and as a fellow of the European Society for Magnetic Resonance in Medicine and Biology.
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