A focused examination of pharmaceutical discoveries and developments through analysis of scientific publications.
A focused examination of pharmaceutical discoveries and developments through analysis of scientific publications.
Dive into the world of drug discovery with this course focusing on real-world case studies from the pharmaceutical industry. Students will analyze five Drug Annotations articles from the Journal of Medicinal Chemistry, covering topics from drug indications to preclinical studies. The course provides a comprehensive look at the drug discovery process, including lead selection, optimization, pharmacodynamics, and safety considerations. Designed for those with a basic understanding of organic chemistry and drug development principles, this self-paced course offers a unique opportunity to apply theoretical knowledge to actual industry research. Through careful reading and analysis of these articles, students will gain valuable insights into the complexities of developing new medications for various conditions, from heart failure to herpes infections. The course structure allows for flexible learning, with each case study requiring about two hours of focused study. Additional video discussions and assessment questions (for verified track students) enhance the learning experience, making this an ideal course for those looking to deepen their understanding of pharmaceutical research and development processes.
Instructors:
English
English
What you'll learn
Analyze real-world drug discovery programs from pharmaceutical companies
Interpret and evaluate Drug Annotations articles from the Journal of Medicinal Chemistry
Understand the process of lead selection and optimization in drug development
Examine pharmacodynamics and pharmacokinetics in the context of specific drug candidates
Assess preclinical safety and PK/ADME studies for various compounds
Explore diverse therapeutic areas including heart failure, cancer, viral infections, and rare diseases
Skills you'll gain
This course includes:
PreRecorded video
Graded assignments, exams
Access on Mobile, Tablet, Desktop
Limited Access access
Shareable certificate
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Created by
Davidson College
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Provided by
Edx
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Top companies offer this course to their employees
Top companies provide this course to enhance their employees' skills, ensuring they excel in handling complex projects and drive organizational success.
There are 5 modules in this course
This course delves into the intricate world of drug discovery through an in-depth examination of five case studies from the pharmaceutical industry. Students will explore real-world drug development programs, focusing on compounds designed to address various medical conditions. The course covers the entire drug discovery process, from initial target identification to preclinical studies. Key topics include lead selection and optimization, understanding drug efficacy and potency, pharmacokinetics, and safety considerations. Each case study provides a comprehensive look at a specific drug candidate, offering insights into the challenges and strategies employed in modern pharmaceutical research. The course structure encourages critical analysis of scientific literature, helping students bridge the gap between theoretical knowledge and practical application in the field of medicinal chemistry.
Discovery of AZD4831
Module 1
Design and discovery of MRTX0902
Module 2
Discovery of pritelivir
Module 3
Discovery of reldesemtiv
Module 4
Sebetralstat (KVD900)
Module 5
Fee Structure
Instructor
7 Courses
Medicinal Chemistry Expert and Educator at Davidson College
Dr. Erland Stevens is a distinguished faculty member in the Chemistry department at Davidson College, bringing a wealth of experience in medicinal chemistry and drug discovery to his role. After earning his Ph.D. from the University of Michigan at Ann Arbor in 1997, specializing in nitrogen heterocycles under Will Pearson, Stevens pursued postdoctoral studies at The Scripps Research Institute with K. Barry Sharpless. Joining Davidson College in 1998, he has since become a cornerstone of the chemistry program, regularly teaching medicinal chemistry to junior and senior undergraduates. Stevens' expertise extends beyond academia, as evidenced by his involvement in the continuing education program at GlaxoSmithKline's Research Triangle Park site in 2006 and 2007. His contributions to the field include authoring the textbook "Medicinal Chemistry: The Modern Drug Discovery Process," published by Pearson Education, which has likely become a valuable resource for students and professionals in the field. Stevens' research focuses on the synthesis and activity of antiviral nucleoside analogues, demonstrating his ongoing commitment to advancing pharmaceutical science. His career exemplifies the integration of academic research, industry relevance, and dedicated teaching in the field of medicinal chemistry.
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